It is used in amino acid infusions. It is often used in combination with iron preparations, vitamins, etc. When used together with vitamin B6, it can improve depression and prevent and treat pellagra. As a sedative for insomnia, it is used in combination with L-dopa for the treatment of Parkinson's disease. It is carcinogenic to experimental animals; adverse reactions include nausea, anorexia, drowsiness, etc. It is forbidden to be used in combination with monoamine oxidase inhibitors.
Uses
As a nutritional supplement. Tryptophan contained in egg white protein, fish meat, corn flour, etc. is a limiting amino acid, and its content is relatively low in grains such as rice. It can be used in combination with lysine, methionine, and threonine for amino acid fortification. Adding 0.02% tryptophan and 0.1% lysine to corn products can significantly improve the protein efficiency ratio. It is an important component of amino acid infusions and comprehensive amino acid preparations. It can be used to treat niacin deficiency.
| Property | Value |
| Melting Point | 289-290 °C (dec.)(lit.) |
| Specific Rotation | -31.1 ° (c=1, H2O) |
| Boiling Point | 342.72°C (rough estimate) |
| Density | 1.34 |
| Bulk Density | 400kg/m³ |
| Refractive Index | -32 ° (C=1, H2O) |
| Storage Condition | 2-8°C |
| Solubility | 20%NH₃:0.1 g/mL at 20 °C, clear, colorless |
| Form | Powder |
| pKa | 2.46 (at 25°C) |
| Color | White to off-white |
| pH Value | 5.5-7.0 (10g/l, H2O, 20°C) |
| Odor | White crystals or colorless powder, slightly bitter taste |
| Biological Source | non-animal source |
| Optical Rotation | [α]20/D 31.5±1°, c = 1% in H2O |
| Water Solubility | 11.4 g/L (25 °C) |
| Merck | 14,9797 |
| BRN | 86197 |
| Stability | Stable. Incompatible with strong acids and strong oxidizing agents. |
| InChIKey | QIVBCDJIJAPQS-VIFVPBQESA-N |
| LogP | 0.704 (est) |
| CAS Database | 73-22-3(CAS DataBase Reference) |
| NIST Chemistry Info | L-Tryptophan(73-22-3) |
| EPA Chemistry Info | L-Tryptophan (73-22-3) |
| Absorption | cut-off at 326nm in 0.5 M HCl at 0.5M |