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Resveratrol #501-36-0

Resveratrol #501-36-0
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Product Parameters
It can inhibit the oxidation of low-density lipoprotein and has potential effects in preventing and treating cardiovascular diseases, preventing cancer, fighting viruses, and regulating immunity. Its functions are mainly reflected in its antioxidant properties.

As a cardiovascular drug, it can lower blood lipids, prevent heart diseases, and also has an anti-AIDS effect.

It is an antioxidant with various activities such as anti-inflammation, anti-thrombosis, cancer prevention, anti-cancer, anti-hyperlipidemia, and antibacterial effects.

Delays aging, regulates blood lipids, protects the cardiovascular and cerebrovascular systems, and resists hepatitis.

Acts as a COX-1 selective inhibitor; a phenolic phytoalexin found in grape skins and other plants, with intracellular antioxidant activity and the ability to activate SIRT1—a NAD+-dependent histone deacetylase involved in the biological origin of mitochondria, as well as enhance the activity of peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) and FOXO. The anti-diabetic, neuroprotective, and anti-adipogenic effects of resveratrol may be mediated through SIRT1 activation.

A COX-1 selective inhibitor. Resveratrol is a phenolic phytoalexin found in grape skins and other plants. It has intracellular antioxidant activity and activates the deacetylase SIRT1. The anti-diabetic, neuroprotective, and anti-lipid properties of resveratrol may all be attributed to the activation of deacetylase SIRT1.

PropertyValue
Melting Point253-255°C
Boiling Point449.1±14.0 °C(Predicted)
Density1.359±0.06 g/cm³(Predicted)
Storage Condition-20°C
SolubilitySoluble in DMSO (up to 25mg/ml) or ethanol (up to 20mg/ml).
FormPowder
pKa9.22±0.10(Predicted)
ColorOff-white
Biological Sourceplant root (bushy knotweed)
Water SolubilitySoluble in water (3 mg/100mL), ethanol (50 mg/mL), DMSO (16 mg/mL), DMF (~65 mg/mL), PBS (pH 7.2) (~100μg/mL), methanol, and acetone (50 mg/mL).
Merck14,8158
StabilityStable for up to 2 years from the date of purchase. DMSO or ethanol solutions can be stored at -20°C for up to 1 month.
InChIInChI=1S/C14H12O3/c15-12-5-2-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
InChIKeyLUKBXSAWLPMMSZ-OWOJBTEDSA-N
SMILESC1(O)=CC(/C=C/C2=CC=C(O)C=C2)=CC(O)=C1
LogP3.139 (est)
CAS Database501-36-0(CAS DataBase Reference)
EPA Chemistry Info1,3-Benzenediol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]- (501-36-0)


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